Encephalitis Lethargica
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چکیده
Encephalitis lethargica (EL) was named and described by Von Economo in 1916, and further detailed in a monograph in 1931 [1] following the pandemic of 1919 to 1926, but for many years was regarded as a phenomenon of the past. In recent years there has been a recurrence of interest in the disease, concerning aetiology and links with post encephalitic parkinsonism. Oliver Sacks described awakening of past cases, but recent papers have described contemporary cases and defined the disease in modern terms. In 2003 we undertook a literature survey to assess the published information on this disease in the last 20 years.
منابع مشابه
A historical analysis of the relationship between encephalitis lethargica and postencephalitic parkinsonism: a complex rather than a direct relationship.
Postencephalitic parkinsonism has been considered unique among disorders with parkinsonian features because it is believed to have a unitary etiology associated with the virus that presumably caused encephalitis lethargica. Careful analysis of the historical record, however, suggests that this relationship is more complex than commonly perceived. In most cases, the diagnosis of acute encephalit...
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The cognitive profile and outcome of Encephalitis Lethargica has not been systematically described in the literature. Treatment has typically focused upon medical management. The first case report of a patient with Encephalitis Lethargica who underwent a systematic programme of cognitive rehabilitation is presented. Initial neuropsychological assessment conducted during her acute presentation i...
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Encephalitis lethargica is an acute encephalopathic illness characterised by sleep disturbance, neuropsychiatric and extrapyramidal symptoms. It is rarely reported in children and the diagnosis is made by exclusion of infective, biochemical, degenerative, autoimmune, toxic or metabolic causes of acute encephalopathy. It is recently postulated to be part of a spectrum of poststreptococcal autoim...
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As the subject of encephalitis lethargica has been much discussed recently in medical circles in Europe, but very little mention of the disease has been made up to now in the Indian papers, the following report of two acute cases which have lately occurred in Calcutta is given in the hope that it may evoke discussion and lead others to report similar cases, so that some estimate can be formed o...
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